GMP Manufacturing

Cell banking

Pilot-scale manufacturing

Commercial manufacturing

TOT BIOPHARM has established a commercial GMP production base for biological drugs, which is equipped with a series of cell bank production lines (independent cell bank workshops) and several independent drug substance production lines. We provide cell bank production (MCB and WCB) and antibody DS manufacturing services in 200 L, 500 L and 2,000 L size, with total capacity over than 20,000 L.

– TOT BIOPHARM uses production equipment of international leading brand, including Cytiva’s single use bioreactors and chromatography systems, as well as Millipore and PALL’s ultrafiltration systems.

– With single use technology and highly flexible production strategy, stages for batches and specifications at the same time can be accommodated.

– With extensive experience, the team has completed dozens of drug substance production, including the successful completion of multiple batches of marketed products.